In a shallow bowl, combine flour, ½ tsp salt, ½ tsp pepper, 1 tsp garlic powder, 1 tsp onion powder, and 1 tsp paprika.
In a second bowl, whisk together eggs, milk, and hot sauce.
In a third bowl, combine panko breadcrumbs with ½ tsp salt.
Dredge chicken pieces in the seasoned flour, shaking off excess. Dip into the egg wash, then coat in panko, pressing to adhere.
Heat about ½ inch of oil in a skillet over medium heat. Fry chicken in batches for 3–4 minutes per side until golden brown and cooked through. Transfer to a paper towel-lined plate or wire rack.